INGREDIENTS
Capsules
350mg nicotinamide riboside chloride (NR) per capsule and HMPC vegetable cellulose capsule.
Powder
350mg nicotinamide riboside chloride (NR) per scoop.
HOW IT WORKS
Nicotinamide riboside is a supplemental form of vitamin B3 that enables the body to produce sufficient amounts of nicotinamide adenine dinucleotide (NAD+).1 As a supplement, it appears to increase the concentration of NAD+ above levels naturally produced when getting vitamin B3 from the diet.2
NAD+ plays an essential role in many of the body's metabolic processes, such as oxidative stress, inflammatory response, and sleep/wake cycles. NAD+ decreases in many tissues throughout the aging process, in times of stress, or during other periods of inflammation.2
Decreased NAD+ levels are thought to increase the risk of several diseases, including the following:
- Cardiovascular disease
- Neurodegenerative diseases (such as Alzheimer's disease)
- Metabolic syndrome (a cluster of conditions that together can lead to heart disease, stroke, and type 2 diabetes)
Conversely, elevated levels of NAD+ lead to increased production of sirtuins. Sirtuins, a family type of enzymes, play an essential regulatory role in many of the body's processes, including the following:
- Stress reduction
- Cell growth
- Sleep/wake cycles
- Cognitive function
- Metabolism7
NR has been shown to increase NAD+ levels in the body. There is interest in researching NR supplementation's effects on aging and diseases that correlate with low levels of NAD+.